Many thanks to John Sheasgreen and colleagues at MatTek Corporation for providing the following references for display at invitroderm.com. The main highlight of this collection is the large number of abstracts about EpiDermÔ , an in vitro model widely used for studies of dermal irritancy and corrosion.

Appa, Y., A.G. Asuncion, M. Podda, M.A. Duke, and S.R. Rachui. An In Vitro Method to Evaluate the Antioxidant Efficacy of Topical Formulations. [Presentation at American Academy of Dermatol. Annual Meeting, 1996].

Bernhofer, L., C. Juneja, and K. Martin. The Use of Mattek Epi-Dermal Equivalent for Prediction of Irritation Potential. J. Invest. Dermatol. 1995. 105(6): 874.

Bernhofer, L., M. Seiberg, and K.M. Martin. Development of An In Vitro Model for the Prediction of Skin Irritation Potential. [Presented at 1997 Congress on In Vitro Biology].

Cannon, C.L., P.J. Neal, J. Kubilus, M. Klausner, D.C. Swartendrubber, C.A. Squier, M.J. Kremer, P.W. Wertz. Lipid and Ultrastructural Characterization of a New Epidermal Model Shows Good Correspondence to Normal Human Epidermis. J. Invest. Dermatol. 1994. 102(4): 641. Abst. #458.

Cannon, C.L., P.J. Neal, J. Kubilus, M. Klausner. Lot-to-Lot Variability of EpiDermÔ , An Epidermal Model for Dermal Irritancy Testing. The Toxicologist 1994. 14(1). Abstract #349.

Cannon, C.L., P.J. Neal, J. Kubilus, M. Klausner, J.W. Harbell, R.D. Curren. Intra- and Interlaboratory Reproducibility (ET-50) of EpiDermÔ , An In Vitro Model for Dermal Irritancy Testing. [Presented at symposium, "Alternatives in the Assessment of Toxicity; Theory & Practice" Aberdeen, MD, May 1994].

Cannon, C.L., P.J. Neal, J. Kubilus, and M. Klausner. New Epidermal Model for Dermal Irritancy Testing. [Presented at J.F. Morgan Research Foundation symposium, "Current Trends in In Vitro Skin Toxicology and Eye Irritancy Testing," April, 1993].

Cannon, C.L., P.J. Neal, J. Kubilus, and M. Klausner. Initial Characterization of a New Model for Dermal Irritancy Testing. [Presented at Tissue Culture Association annual meeting, June, 1993].

Cannon, C.L., P.J. Neal, J.A. Southee, J. Kubilus, and M. Klausner. New Epidermal Model for Dermal Irritancy Testing. [Presented at symposium, "Practical In Vitro Toxicology III", July, 1993].

Cannon, C.L., P.J. Neal, J. Kubilus, M. Klausner, D. C. Swartendruber, C.A. Squier, and P.W. Wertz. Lipid Characterization of a New Epidermal Model for Skin Irritancy and Penetration Studies. [Presented at "World Congress on Alternatives and Animal Use in the Life Sciences." November, 1993].

Correll, L., V. Keeble and M. Ehrich. Effect of Laundering on Ability of Glove Fabrics to Inhibit the Penetration of Organophosphate Insecticides Through an Artificial Skin Model. The Toxicologist 1995. 15(1): Abstract #133.

Daddona, P. New Drug Delivery Systems: Validation of In Vitro Models. ATLA 1996. 24: 111.

Doyle, J.M., W. Dressler, and S.R. Rachui. Evaluation of Two In Vitro Human Skin Equivalents (The EpiDermÔ and Skin2Ô Model ZK1300) for Assessing the Skin Irritation Potential of Personal Care Products and Chemicals. [Presented at symposium, "Alternatives in the Assessment of Toxicity; Theory & Practice," Aberdeen, MD, May 1994].

Earl, L.K., T.J. Hall-Manning, G.H. Holland, A. Irwin, J.P. McPherson, and J.A. Southee. Skin Irritation Potential of Surfactant Mixtures: Using Relevant Doses in In Vitro Systems. ATLA 1996. 24: 249, Abstract #73.

Fares, H.M., S. Chatterjee, and M. Hayward. In Vitro Permeation and Irritation of Benzoyl Peroxide - Containing Products. [Presented at American Association of Pharmaceutical Scientists 10th Annual Meeting, November, 1995, Paper NO. PDD 7352].

Hall, B., R. Osborne, and M.A. Perkins. Comparisons of In Vitro and In Vivo Skin Responses to Surfactants with a Range of Irritancy Potential. [Presented at "International Symposium on Irritant Contact Dermatitis" Poster #44P, April 1994].

Harbell, J.W., J.A. Southee, C.L. Cannon, P.J. Neal, J. Kubilus, and M. Klausner. Inter- and Intralaboratory Reproducibility of a Three Dimensional Human Epidermal Model - EpiDermÔ . The Toxicologist 1994. 14(1): Abstract #350.

Hayden, P.J. Cytokine and Lipid Mediator Release from In Vitro Skin Models Following Detergent Treatment or Physical Wounding. J. Invest. Dermatol. 1996. 106(4): 936. Abst. #782.

Klausner, M., J. Kubilus, and P.J. Neal. Initial Characterization of an Epidermal Model Containing Functional Melanocytes. J. Invest. Dermatol. 1995. 104(4): 616. Abst. #370.

Klausner, M., J. Kubilus, H.A. Ricker, and P.J. Neal. UVB Irradiation of an Organotypic Skin Model, EpiDermÔ , Results in Significant Release of Cytokines. The Toxicologist 1995. 15(1). Abstract #1745.

Klausner, M., J. Kubilus, P. Neal, C. Cannon, H. Sennott, and P. Ogle. A Reproducible Structurally Appropriate Skin Model for Dermal Irritancy and Efficacy Testing. ATLA 1996. 24: 263, Abstract #100.

Klausner, M., P. Neal, and J. Kubilus. Initial Results with Epi-201, A Developing In Vitro Model of Human Epidermis. J. Invest. Dermatol. 1998. 110(4):558, Abst.#513.

Kreihuber, E., Y. Takagi, G. Imokawa, P.M. Elias, and W.M. Holleran. Localization of Glucocerebrosidase Activity in Mammalian Epidermis by In Situ Zymography. J. Invest. Dermatol. 1997. 108(4): 594. Abst #337.

Kubilus, J., C.L. Cannon, P.J. Neal, H.A. Ricker, and M. Klausner. Cytokine Response of the Epiderm Skin Model to Topically Applied Irritants and Toxicants. In Vitro Toxicol. 1996. 9(2): 157.

Lake, L.K., J.E. Swanson, J. Kubilus, P.J. Neal, and M. Klausner. Use of An In Vitro Skin Model to Predict Chemical Corrosivity. The Toxicologist 1994. 14(1): Abstract #340.

Lee, R.D., H.S. White, and E.R. Scott. Visualization of Iontophoretic Transport Paths in Cultured and Animal Skin Models. J. Pharmaceutical Sciences 1996. 85(11): 1186.

Liebsch, M., Barrabas, C., Traue, D., and H. Spielmann (1997). Development of a New In Vitro Test for Dermal Phototoxicity Using a Model of Reconstituted Human Epidermis (EpiDermÔ ). ALTEX 14: 165-174.

Limardi, L.C., E.E.Sikorski, and G.F. Gerberick. Cytokine Gene Expression in the Mattek EpiDermÔ Cultures. J. Invest. Dermatol. 1996. 106(4): 939. Abst. #803.

Mershon, M.M., L.S.Rhoads, and R.G. Van Buskirk. Alamar Blue Discloses Latent Toxicity of Vesicant in Human Epidermal Model and Cells. J. Toxicol. - Cut. & Ocular Toxicol. 1994. 13(4): 289.

Nabi, Z., A. Tavakkol, N. Soliman, and T.G. Polefka. Bioconversion of Tocopherol Acetate to Tocopherol in Human Skin Organ Culture Models. J. Invest. Dermatol. 1998. 110(4):679, Abst. #1239.

Ogle, P., H. Sennott, P.J. Neal, C.L. Cannon, J. Kubilus, and M. Klausner. Intra- and Inter-Lot Variability of EpiDermÔ , An Epidermal Model for Dermal Research and Testing. J. Invest. Dermatol. 1996. 106(4): 868. Abst. #377.

Perkins, M.A. and R. Osborne. Application of an In Vitro Method for Skin Corrosion Testing to a Variety of Commercially Available Skin Cultures. J. Invest. Dermatol. 1994. 102(4): 641. Abstract #707.

Perkins, M.A., R. Osborne, and G.R. Johnson. Development of Histopathologic Criteria for Assessing In Vitro Skin Corrosion. The Toxicologist 1995. 15(1): Abstract #650.

Perkins, M.A. , R. Osborne, and G.R. Johnson. Development of an In Vitro Method for Skin Corrosion Testing. Fund. Appl. Toxicol. 1996. 31: 9-18.

Perkins, M.A., R. Osborne, and M.K. Robinson, F. Rana, A. Ghassemi, and B. Hall. Comparison of In Vitro and In Vivo Human Skin Responses to Consumer Products and Ingredients with a Range of Irritancy Potential. The Toxicologist 1996. 30(1): 168. Abstract #864.

Rachui, S.R., W.D. Robertson, M.A. Duke, and R. Allen. A Comparison Study of Four In Vitro Phototoxicity Systems. [Presentation at The CTFA 52nd Scientific Conference, Orlando, FL, November 1995].

Rachui, S.R., W.D. Robertson, M.A. Duke, and R. Allen. An In Vitro Method to Evaluate the Efficacy of Antioxidants. [Presented at CTFA Annual Meeting, San Francisco, CA October 1994].

Sennott, H., A. Makwana, J. Kubilus, and M. Klausner. Presence of Hydrocortisone Dramatically Affects Cytokine Production Following UV Irradiation in 3-Dimensional Skin Model EpiDermÔ . J. Invest. Dermatol. 1997. 108(4): 665. Abst. #765.

Sikorski, E.E., G.F. Gerberick. And L.C. Limardi. Modulation of Cytokine Message in the EpiDermÔ In Vitro Skin Model Following Treatment with Contact Allegens and Skin Irritants. The Toxicologist. 1997. 36(1): 192. Abstract #977.

Wolf, B.A., S.C. Kwan, J.A. Moral, and L. Rheins. Development of In Vitro Methods for Evaluating the Epidermal and Dermal Effects of Alpha Hydroxy and Amides. J. Invest. Dermatol. 1995. 104(4): 639. Abstract #511.

Zhao, J. F., Y.J. Zhan, J. Kubilus, X.H. Jin, D.R. Bickers, and Z.Y. Wang. Reconstituted 3-Dimensional Human Skin, A New In Vitro Model for Skin Carcinogenesis Study. J. Invest. Dermatol. 1998. 110(4): 525. Abst. #319.