Merci to Dr. Roland Roguet and colleagues for sharing the following references for display at http://www.invitroderm.com !

Botham, P., L.K. Earl, J. Fentem, R. Roguet, and JJM Van de Sandt. Alternative Methods for Skin Irritation Testing: The Current Status. ECVAM Skin Irritation Task Force Report 1. ATLA 1998. 26: 195-211.

Cohen, C., C. Selvi-Bignon, A. Barbier, A. Rougier, A. Lacheretz et R. Roguet. Measurement of Proinflammatory Mediators on Keratinocytes in Culture: A Predictive Assessment of Cutaneous Irritation. 1994. dans "In Vitro Skin Toxicology", A. Rougier, A. Goldberg, and H.I. Maibach Eds. Mary Ann Liebert, New York pp. 83-96.

Cohen, C., G. Dossou, A. Rougier and R. Roguet. Measurement of Inflammatory Mediators Produced by Human Keratinocytes In Vitro: A Predictive Assessment of Cutaneous Irritation. Toxic. In Vitro. 1991. 5(5/6): 407-410.

Cohen, C., K.G. Dossou, A. Rougier, and R. Roguet. EpiSkin, an In Vitro Model for the Evaluation of Phototoxicity and Sunscreen Photoprotective Properties. Toxic. In Vitro 1994. 8(4): 669-671.

Cotovio, J., J. LeClaire, and R. Roguet. Cytochrome P-450 Dependent Enzyme Activities in Normal Adult Human Keratinocytes and Transformed Human Keratinocytes. In Vitro Toxic. 1997. 10: 207-216.

Cotovio, J., R. Roguet, FX Pion, A. Rougier, and J. LeClaire. Effect of Imidazole Derivatives on Cytochrome P-450 Enzyme Activities in a Reconstructed Human Epidermis. Skin Pharmacol. 1996. 9: 242-249.

Prunieras, M. et R. Roguet. Toxicite¢ Cutanee in Vitro. dans "Toxicologie Cellulaire In Vitro Methodes et Applications". 1995. M. Adolphe et M. Guillouzo. Eds. INSERM Editions pp. 191-236.

Raffali, F., A. Rougier, and R. Roguet. Detection, Measurement and Modulation of Cytochrome P-450 Dependent Enzyme Activity in Cultured Human Keratinocytes. Skin Pharmacol. 1994. 7: 345-354.

Roguet, R., C. Cohen, C. Robles, P. Courtellemont, M. Tolle, J.P. Guillot and X. Pouradier Duteil. An Interlaboratory Study of the Reproducibility and Relevance of EpiSkin, A Reconstructed Human Epidermis, in the Assessment of Cosmetics Irritancy. Toxic. In Vitro. 1998. 12: 295-304.

Roguet, R. J. Cotovio, J. LeClaire. Reconstructed Skin for In Vitro Cutaneous Pharmacotoxicology: Example of Metabolic Studies. In Vitro Toxic. 1997. 10: 3-9.

Roguet, R. and H. Schafer. Overview of In Vitro Cell Culture Technologies and Pharmaco-toxicological Applications. Toxic. In Vitro 1997. 11: 591-599.

Roguet, R., C. Cohen, J. LeClaire, and A. Rougier. Utilisation d'un Epiderme Reconstruit dans L'evaluation des Effets Cytotoxiques des Rayonements UV. Les Nouvelles Dermatologiqes. 1996. 15: 384-390.

Roguet, R. Cutaneous Pharmacotoxicology In Vitro. dans "In Vitro Methods in Pharmaceutical Research". 1996. J.V. Castell and M.J. Gomez Lechon Eds. Academic Press. London Ed. pp. 242-261.

Roguet, R. Interet des Peaux Reconstruites en Cosmetologie. Cosmetologie 1996. 13: 38-43.

Roguet, R., C. Cohen, J. LeClaire, and A. Rougier. Utilisation de Modeles de Peaux Reconstruites dans L'e valuation de la Securite et del L'efficacite' des Produits Cosmetiques. Les Nouvelles Dermatologiqes 1995. 14: 2-3.

Roguet, R., C. Cohen, J. LeClaire. The Use of a Reconstructed Human Epidermis, EpiSkin for the Assessment of Safety and Efficacy of Cosmetic Products. In Vitro Toxic. 1995. 8(4): 427-429.

Roguet, R., C. Cohen, J. LeClaire et A. Rougier. Utilisation d'un Epiderme Reconstruit dans L'evaluation des Effets Cytotoxiques des Rayonements UV. Les Nouvelles Dermatologiqes. 1995. 14: 2-3, p 39.

Roguet, R., C. Cohen, A. Rougier, and J. LeClaire. Measurement of Proinflammatory Mediator Production by Cultured Keratinocytes as a Predictor of Xenobiotic Skin Irritancy. 1995. dans "Irritant dermatitis: New clinical and Experimental Aspects". Current Problems in Dermatology. P. Elsner and H.I. Maibach Eds. Tomas Karger, Basel.

Roguet, R., J. Cotovio, P. Kremers, A. Rougier, X. Pouradier Duteil and J. LeClaire. Cytochrome P-450-Dependent Enzyme Activities and Testosterone Metabolism in a Reconstituted Human Epidermis. In Vitro Toxic. 1995. 8(1): 97-104.

Roguet, R., M. Regnier, C. Cohen, K.G. Dossou and A. Rougier. The Use of In Vitro Reconstituted Human Skin in Dermotoxicity. Toxic. in Vitro 1994. 8(4): 635-639.

Roguet, R., C. Cohen, and A. Rougier. A Reconstituted Human Epidermis to Assess Irritation, Photoirritation and Photoprotection in Vitro. 1994. dans "In Vitro Skin Toxicology", A. Rougier, A. Goldberg, and H.I. Maibach Eds. Mary Ann Liebert, New York pp. 141-149.

Roguet, R., C. Cohen, K.G. Dossou, and A. Rougier. EpiSkin, A Reconstituted Epidermis for Assessing in Vitro the Irritancy of Topically Applied Compounds. Toxic. In Vitro. 1994. 8(2): 283-291.

Roguet, R., Dossou, K.G., and A. Rougier. Use of In Vitro Skin Recombinants to Evaluate Cutaneous Toxicity: A Preliminary Study. J. Toxicol. - Cut. Ocular Toxicol. 1992. 11(4): 305-315.