Merci to Bart De Wever and colleagues at SkinEthic Laboratories (http://www.skinethic.com) who provided the following references about some innovative work with reconstructed epidermis and epithelium to invitroderm.com! See Photo Gallery for photographs of this research methodology.
Berna, N., A. Coquette, A. Vandenbosch, and Y. Poumay. Use of Reconstructed Epidermis to Assess Keratinocyte Activation by Skin Irritant and Sensitizing Compounds. J. Invest. Dermatol. 1998. 110:657.
Bernard, F-X., C. Barrault, A. Deguercy, and M. Rosdy. The Reconstructed Epidermis, SkinEthicâ , as a Model for Studying the Effects of Compounds on Epidermal Growth And/Or Differentiation. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P060.
Bonnabry, C., E. Beyssac, M. Rosdy, D. Saboureau, and J.M. Aiache. Reconstituted Epidermis, A Model Membrane for Testing in Vitro Release Kinetics of Progesterone Using Franz Cells: Comparison with Human and Hairless Mouse Skin. Perspectives in Percutaneous Penetration. 1998. Vol. 6A, pg. 90.
Botham, P.A., L.K. Earl, J.H. Fentem, R. Roguet, and J.J.M. van de Sandt. Alternative Methods for Skin Irritation Testing: the Current Status. ATLA 1998. 26: 195-211.
Coquette, A. Differential Expression and Release of Cytokines by an In Vitro Reconstructed Human Epidermis Following Exposure to Skin Irritant and Sensitizing Chemicals. Presentation at IBC's Third Annual Symposium on "In Vitro Testing Methods for Skin Care and Cosmetic Products". Nov. 16-17, 1998. Washington, DC USA
De Fraissinette, A., S. Chibout, V. Picarles, M. Kolopp, J. Meingassner, M.E. Ebelin, A. Spake, S. Osborne, P. Burtin, and R.A. Ettlin. Predictivity of an In Vitro Screening Test of Contact Irritative Potential for Topical Vehicles Using a Human Reconstructed Epidermis Model (SkinEthicâ ). Perspectives in Percutaneous Penetration. 1998. Vol. 6A, pg. 97.
Doucet, O., C. Robert, A.A. Vink, L. Roza, B. Bertino, and L. Zastrow. Interest of a Post-Irradiation Treatment in Reducing Skin Photodamages Induced By Acute UVB Exposure. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P211.
Doucet, O., C. Robert, A.M. Orcet, and L. Zastrow. In Vitro Assessment of the Self-Tanning Efficacy of Formulated Cosmetics Using a Skin Culture Model. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P065.
Doucet, O., C. Robert, and L. Zastrow. Use of a Serum-free Reconstituted Epidermis as a Skin Pharmacological Model. Toxic. in Vitro. 1996. 10: 305-313.
Doucet, O., N. Garcia, and L. Zastrow. Alteration in the Skin Barrier Function Using Organic Solvents in Reconstituted Epidermis and Excised Human Skin. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P213.
Doucet, O., N. Garcia, and L. Zastrow. Impairment of the Barrier Function of Excised Human Skin and Reconstituted Epidermis Following Acute Pretreatments with Acetone/Ether. Perspectives in Percutaneous Penetration. 1998. Vol. 6A., pg. 42.
Doucet, O., N. Garcia, and L. Zastrow. Skin Culture Model: A Possible Alternative to the Use of Excised Human Skin for Assessing In Vitro Percutaneous Absorption. Toxic. in Vitro. 1998. 12: 423-430.
Fartasch, M. and M. Rosdy. Maturation of the Epidermal Barrier in Air-Exposed Keratinocyte Cultures: A Time Course Study. J. Invest. Dermatol. 1996. Abstract #423. 107(3): 518.
Fartasch, M., M. Ponec, and M. Rosdy. The Development of a Structurally Competent Epidermal Barrier in Air-Exposed Keratinocyte Cultures: A Time Course Study. J. Invest. Dermatol. 1996. Abstract #3. 107(4): 656.
Fitoussi, I. Mary, and S.A. Clarins. The Use of the SkinEthicâ Reconstructed Human Epidermis as a Predictive Tool for the Determination of the Skin Irritation Potential of Perfumes and Perfume Products in Vitro. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P068.
Fitoussi, R., I. Mary, and S.A. Clarins. The SkinEthicâ Reconstituted Human Epidermis: An In Vitro Model for Studying the Formation of 'Sun Burn Cells'. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P062.
Gysler, A. Biotransformation and Penetration of Topical Glucocorticoids in Different Types of Reconstructed Epidermis and Excised Human Skin. Presentation at IBC's Third Annual Symposium on "In Vitro Testing Methods for Skin Care and Cosmetic Products". Nov. 16-17, 1998. Washington, DC USA
Gysler, A., U. Bacher, and M. Schafer-Korting. Biotransformation and Penetration of Topical Glucocorticoids in Reconstructed Epidermis and Excised Human Skin. Perspectives in Percutaneous Penetration. 1998. Vol. 6A, pg 58.
Martin, K. M. UV Induced MMP-1 Production: An In Vitro Model for Assessing Photoprotection. Presentation at IBC's Third Annual Symposium on "In Vitro Testing Methods for Skin Care and Cosmetic Products". Nov. 16-17, 1998. Washington, DC USA
Meloni, M. E. Santirocco, and M. Lavazza. A Study of the Redox Status of the Intracellular Glutathione on a Reconstructed Epidermis Model. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P193.
Rosdy, M. and L.-C. Clauss. Terminal Epidermal Differentiation of Human Keratinocytes Grown in Chemically Defined Medium on Inert Filter Substrates at the Air-Liquid Interface. J. Invest. Dermatol. 1990. 95: 409-414.
Rosdy, M., B. Bertino, V. Butet, S. Gibbs, M. Ponec, and M. Darmon. Retinoic Acid Inhibits Epidermal Differentiation When Applied Topically on the Stratum Corneum of Epidermis Formed In Vitro by Human Keratinocytes Grown on Defined Medium. In Vitro Toxicol. 1997. 10(1): 39-47.
Rosdy, M., Fartasch, M., and M. Ponec. Structurally and Biochemically Normal Permeability Barrier of Human Epidermis Reconstituted in Chemically Defined Medium. J. Invest. Dermatol. 1996. Abstract #52. 107(4): 664.
Rosdy, M., M. Fartasch, and M. Darmon. Normal Permeability Barrier to Tritiated Water in Reconstituted Human Epidermis. Poster Presentation. Prediction of Percutaneous Penetration meeting. April 2-5, 1997. La Grande Motte, France.
Schaller, M., W. Schafer, H.C. Korting, and B. Hube. Differential Expression of Secreted Aspartyl Proteinases in a Model of Human Oral Candidosis and in Patient Samples from the Oral Cavity. Molecular Microbiology 1998. 29(2): 605-615.
Tokgoz, N.S., G. Marginean-Lazar, A. Ponte, and A.E. Fructus. Use of Synthetic Skin for In-Vitro Evaluation of Photoprotective Efficacy of Sunscreens: Application to Different Type of Emulsions. IN: Proceedings of the 20th International Federation of Societies of Cosmetic Chemists Congress. P040.